Gluco-sulfatase
نویسندگان
چکیده
منابع مشابه
Applications of Gluco - oligosaccharide Oxidase
The nascent study of carbohydrate-active enzymes is now influencing a variety of industries at the commercial scale, particularly in processing lignocellulosic biomass for the production of fuels, materials, and other commodities. These enzymes are highly specific and can modify sugars with selectivity unmatched by chemical processes. Our group has worked extensively with gluco-oligosaccharide ...
متن کاملSUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies.
Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters. Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids. The catalytic activity of sulfatases resides in a unique formylglycine residue in their active site generated by the post-translational modification of a highly conserved cysteine...
متن کاملExtracellular gluco-oligosaccharide degradation by Caulobacter crescentus.
The oligotrophic bacterium Caulobacter crescentus has the ability to metabolize various organic molecules, including plant structural carbohydrates, as a carbon source. The nature of β-glucosidase (BGL)-mediated gluco-oligosaccharide degradation and nutrient transport across the outer membrane in C. crescentus was investigated. All gluco-oligosaccharides tested (up to celloheptose) supported gr...
متن کاملDevelopment of steroid sulfatase inhibitors.
Hydrolysis of biologically inactive steroid sulfates to unconjugated steroids by steroid sulfatase (STS) is strongly implicated in rendering estrogenic stimulation to hormone-dependent cancers such as those of the breast. Considerable progress has been made in the past two decades with regard to the discovery, design and development of STS inhibitors. We outline historical aspects of their deve...
متن کاملMultiple sulfatase deficiency: catalytically inactive sulfatases are expressed from retrovirally introduced sulfatase cDNAs.
Multiple sulfatase deficiency (MSD) is an inherited lysosomal storage disease characterized by the deficiency of at least seven sulfatases. The basic defect in MSD is thought to be in a post-translational modification common to all sulfatases. In accordance with this concept, RNAs of normal size and amount were detected in MSD fibroblasts for three sulfatases tested. cDNAs encoding arylsulfatas...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Imperial Academy
سال: 1931
ISSN: 0369-9846,1881-1140
DOI: 10.2183/pjab1912.7.269